Products
ESR2 antibody
- Product Name
- ESR2 antibody
- Catalogue No.
- FNab02866
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- estrogen receptor 2 (ER beta)
- Alternative Names
- ESTRB antibody, NR3A2 antibody
- UniProt ID
- Q92731
- Observed MW
- 55-60 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab02866( ESR2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab02866(ESR2 antibody) at dilution of 1:50
- Background
- This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
