Products

ERK1/2 antibody

Synonyms:ERK antibody, ERK 2 antibody, ERK1/2 antibody, ERK2 antibody, ERT1 antibody, MAP kinase 1 antibody, MAP kinase 2 antibody, MAP kinase isoform p42 antibody, MAPK 1 antibody, MAPK 2 antibody, MAPK1 antibody, MAPK2 antibody, p40 antibody, p41 antibody, p41mapk antibody, p42 MAPK antibody, P42MAPK antibody, PRKM1 antibody, PRKM2 antibody
Catalogue No.:FNab02845Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ERK1/2 antibody
Catalogue No.
FNab02845
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
mitogen-activated protein kinase 1
Alternative Names
ERK antibody, ERK 2 antibody, ERK1/2 antibody, ERK2 antibody, ERT1 antibody, MAP kinase 1 antibody, MAP kinase 2 antibody, MAP kinase isoform p42 antibody, MAPK 1 antibody, MAPK 2 antibody, MAPK1 antibody, MAPK2 antibody, p40 antibody, p41 antibody, p41mapk antibody, p42 MAPK antibody, P42MAPK antibody, PRKM1 antibody, PRKM2 antibody
UniProt ID
P28482
Observed MW
40 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab02845(ERK1/2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab02845( ERK1/2 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Background
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.