Products

ER antibody

Synonyms:DKFZp686N23123 antibody, ER antibody, ER alpha antibody, Era antibody, ESR antibody, ESR1 antibody, ESRA antibody, Estradiol receptor antibody, Estrogen receptor antibody, estrogen receptor 1 antibody, NR3A1 antibody
Catalogue No.:FNab02822Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ER antibody
Catalogue No.
FNab02822
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
estrogen receptor 1
Alternative Names
DKFZp686N23123 antibody, ER antibody, ER alpha antibody, Era antibody, ESR antibody, ESR1 antibody, ESRA antibody, Estradiol receptor antibody, Estrogen receptor antibody, estrogen receptor 1 antibody, NR3A1 antibody
UniProt ID
P03372
Observed MW
70 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:1000 - 1:4000; IHC: 1:50 - 1:200
Validated Images
hela cells were subjected to SDS PAGE followed by western blot with FNab02822( ER Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue using FNab02822(ESR1 antibody) at dilution of 1:100
Background
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.