Products
Endothelin 1 antibody
- Product Name
- Endothelin 1 antibody
- Catalogue No.
- FNab02763
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- endothelin 1
- Alternative Names
- EDN1 antibody, endothelin 1 antibody, ET 1 Big endothelin 1 antibody, ET1 antibody, HDLCQ7 antibody, PPET1 antibody, Preproendothelin 1 antibody
- UniProt ID
- P05305
- Observed MW
- 24 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab02763( EDN1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab02763(EDN1 antibody) at dilution of 1:50
- Background
- This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
