Products

EDEM2 antibody

Synonyms:C20orf31 antibody, C20orf49 antibody
Catalogue No.:FNab02632Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
EDEM2 antibody
Catalogue No.
FNab02632
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
ER degradation enhancer, mannosidase alpha-like 2
Alternative Names
C20orf31 antibody, C20orf49 antibody
UniProt ID
Q9BV94
Observed MW
60-65 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab02632( EDEM2 Antibody) at dilution of 1:300
Background
Initiates the endoplasmic reticulum-associated degradation(ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2(PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.