Products
DNMT3A antibody
- Product Name
- DNMT3A antibody
- Catalogue No.
- FNab02484
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- DNA (cytosine-5-)-methyltransferase 3 alpha
- Alternative Names
- DNMT3A2 antibody
- UniProt ID
- Q9Y6K1
- Observed MW
- 95 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02484(DNMT3A antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab02484(DNMT3A antibody) at dilution of 1:100
- Background
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
