Products
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DKC1 antibody
- Product Name
- DKC1 antibody
- Catalogue No.
- FNab02400
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- dyskeratosis congenita 1, dyskerin
- Alternative Names
- NOLA4 antibody
- UniProt ID
- O60832
- Observed MW
- 43 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab02400(DKC1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab02400(DKC1 Antibody) at dilution of 1:100
- Background
- This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
