mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab02265(DCK antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human uterine cancer using FNab02265(DCK antibody) at dilution of 1:100
Background
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.