Products

DBI antibody

Synonyms:DBI antibody, ACBD1 antibody, ACBP antibody, CCK-RP antibody, EP antibody, acyl-CoA-binding protein antibody
Catalogue No.:FNab02256Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
DBI antibody
Catalogue No.
FNab02256
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)
Alternative Names
DBI antibody, ACBD1 antibody, ACBP antibody, CCK-RP antibody, EP antibody, acyl-CoA-binding protein antibody
UniProt ID
P07108
Observed MW
12 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab02256(DBI antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human Lung cancer using FNab02256(DBI antibody) at dilution of 1:50
Background
This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.