Products

CYP51A1 antibody

Synonyms:CYP51 antibody
Catalogue No.:FNab02176Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CYP51A1 antibody
Catalogue No.
FNab02176
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
cytochrome P450, family 51, subfamily A, polypeptide 1
Alternative Names
CYP51 antibody
UniProt ID
Q16850
Observed MW
63 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab02176(CYP51A1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver using FNab02176(CYP51A1 antibody) at dilution of 1:100
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.