CUL4B antibody

Synonyms:KIAA0695 antibody
Catalogue No.:FNab02079Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, IF, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CUL4B antibody
Catalogue No.
FNab02079
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
cullin 4B
Alternative Names
KIAA0695 antibody
UniProt ID
Q13620
Observed MW
115 kDa
Application
Tested Applications
ELISA, IHC, IF, WB
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab02079(CUL4B antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab02079(CUL4B antibody) at dilution of 1:100
Background
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.