CUL3 antibody

Synonyms:KIAA0617 antibody
Catalogue No.:FNab02075Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CUL3 antibody
Catalogue No.
FNab02075
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
cullin 3
Alternative Names
KIAA0617 antibody
UniProt ID
Q13618
Observed MW
85 kDa
Application
Tested Applications
ELISA, IHC, WB, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab02075( CUL3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate using FNab02075(CUL3 antibody) at dilution of 1:100
Background
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.