Products
Claudin 3 antibody
- Product Name
- Claudin 3 antibody
- Catalogue No.
- FNab01738
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- claudin 3
- Alternative Names
- C7orf1 antibody, claudin 3 antibody, Claudin3 antibody, CLDN3 antibody, CPE R 2 antibody, CPE R2 antibody, CPE receptor 2 antibody, CPETR2 antibody, HRVP1 antibody, RVP1 antibody
- UniProt ID
- O15551
- Observed MW
- 21 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Validated Images
mouse colon tissue were subjected to SDS PAGE followed by western blot with FNab01738( Claudin 3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab01738( Claudin 3 Antibody) at dilution of 1:100
- Background
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
