CHMP2B antibody

Catalogue No.:FNab01659Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IF, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CHMP2B antibody
Catalogue No.
FNab01659
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
chromatin modifying protein 2B
UniProt ID
Q9UQN3
Observed MW
28 kDa
Application
Tested Applications
ELISA, WB, IF, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab01659(CHMP2B antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gastric cancer using FNab01659(CHMP2B antibody) at dilution of 1:50
Background
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.