MCF7 cells were subjected to SDS PAGE followed by western blot with FNab01535(CDC5L antibody) at dilution of 1:1000
Immunofluorescence analysis of A549 cells using FNab01535(CDC5L antibody) at dilution of 1:50
Background
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.