CD8A antibody

Synonyms:CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody
Catalogue No.:FNab09850Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CD8A antibody
Catalogue No.
FNab09850
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
CD8A
Alternative Names
CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody
UniProt ID
P01732
Observed MW
30 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with FNab09850(CD8A antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human tonsil using FNab09850(CD8A antibody) at dilution of 1:100
Background
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.