Products
CD3 epsilon antibody
- Product Name
- CD3 epsilon antibody
- Catalogue No.
- FNab01458
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CD3e molecule, epsilon (CD3-TCR complex)
- Alternative Names
- CD3 antibody, CD3 epsilon antibody, CD3E antibody, CD3-epsilon antibody, T3E antibody, TCRE antibody
- UniProt ID
- P07766
- Observed MW
- 23 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01458(CD3E antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01458( CD3E Antibody) at dilution of 1:200 Heat mediated antigen retrieved with Tris-EDTA buffer, pH9.0
- Background
- The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
