anti- CD150 antibody(PE conjugated)

Manual
  • Specifications
Product Information
Product name

anti- CD150 antibody(PE conjugated)

Catalogue No.

FNab09790

Size

100µg

Form

liquid

Purification

Protein G purified

Purity

≥95% as determined by SDS-PAGE

Host

Rat

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.)

Background

CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM
(signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane
molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells.
The expression is upregulated upon activation. CD150 expression has been shown to be
maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150.
Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially
when co-stimulated through the TCR. CD150 associates with the src homology
2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be
involved in signal transduction. In combination with CD48, CD150 is a useful marker for
hematopoieticstem cell studies.

Immunogen Information
Immunogen

signaling lymphocytic activation molecule family member 1

Synonyms

CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906

Application
Specificity

Mouse

Tested Application

FC

Recommended dilution

1:10-1:50

Uniprot information
Uniprot ID

Q9QUM4

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Hotline

027-87384275