Products
CD138/Syndecan-1 antibody
- Product Name
- CD138/Syndecan-1 antibody
- Catalogue No.
- FNab01423
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- syndecan 1
- Alternative Names
- CD138 antibody, SDC antibody, SYND1 antibody, syndecan antibody
- UniProt ID
- P18827
- Observed MW
- 32 kDa, 85-120 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab01423(SDC1, CD138 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney cancer slide using FNab01423( SDC1, CD138 Antibody) at dilution of 1:200
- Background
- The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
