Products
Cardiac Troponin I antibody
- Product Name
- Cardiac Troponin I antibody
- Catalogue No.
- FNab01273
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- troponin I type 3 (cardiac)
- Alternative Names
- Cardiac troponin I antibody, cTnI antibody, RCM1 antibody, TNNC1 antibody, TNNI3 antibody, troponin I type 3 (cardiac) antibody, Troponin I antibody, cardiac muscle antibody
- UniProt ID
- P19429
- Observed MW
- 26 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
rat heart tissue were subjected to SDS PAGE followed by western blot with FNab01273( TNNI3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human heart using FNab01273(TNNI3 antibody) at dilution of 1:50
- Background
- Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
