Products

BMPR2 antibody

Synonyms:PPH1 antibody
Catalogue No.:FNab00923Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
BMPR2 antibody
Catalogue No.
FNab00923
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
bone morphogenetic protein receptor, type II(serine/threonine kinase)
Alternative Names
PPH1 antibody
UniProt ID
Q13873
Observed MW
120kd,97kd
Application
Tested Applications
ELISA, WB, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:500-1:1000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00923(BMPR2 antibody) at dilution of 1:1000
IP Result of anti-BMPR2 (IP:FNab00923, 4ug; Detection:FNab00923 1:500) with mouse brain tissue lysate 6500ug.
Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.