Products
BMP3 antibody
- Product Name
- BMP3 antibody
- Catalogue No.
- FNab00918
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- bone morphogenetic protein 3
- Alternative Names
- BMP3A antibody
- UniProt ID
- P12645
- Observed MW
- 53 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Validated Images
Recombinant protein were subjected to SDS PAGE followed by western blot with FNab00918( BMP3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat heart using FNab00918( BMP3 Antibody) at dilution of 1:50
- Background
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.
