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BMP2 antibody
- SPECIFICATIONS
- CITATIONS
- Product Name
- BMP2 antibody
- Catalogue No.
- FNab00917
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- bone morphogenetic protein 2
- Alternative Names
- BMP2A antibody
- UniProt ID
- P12643
- Observed MW
- 45 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00917(BMP2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab00917 (BMP2 Antibody) at dilution of 1:50
- Background
- Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.
IF: 4.183
- Journal:
- International Journal of Molecular Sciences
- Cited Date:
- 2020-04-30
- Product: