Products

BCS1L antibody

Synonyms:BCS1 antibody
Catalogue No.:FNab00856Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
BCS1L antibody
Catalogue No.
FNab00856
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
BCS1-like (yeast)
Alternative Names
BCS1 antibody
UniProt ID
Q9Y276
Observed MW
48 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab00856(BCS1L antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab00856(BCS1L antibody) at dilution of 1:50
Background
This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Several alternatively spliced transcripts encoding two different isoforms have been described.