Products

BAD antibody

Synonyms:BBC6 antibody, BCL2L8 antibody
Catalogue No.:FNab00784Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
BAD antibody
Catalogue No.
FNab00784
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
BCL2-associated agonist of cell death
Alternative Names
BBC6 antibody, BCL2L8 antibody
UniProt ID
Q92934
Observed MW
16 kDa
Application
Tested Applications
ELISA, IHC, WB, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab00784(BAD antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate hyperplasia tissue slide using FNab00784( BAD Antibody) at dilution of 1:200
Immunofluorescence analysis of HeLa cells using FNab00784( BAD Antibody). Blue: DAPI for nuclear staining.
Background
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.