Products
ATP7B antibody
- Product Name
- ATP7B antibody
- Catalogue No.
- FNab09849
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ATP7B
- Alternative Names
- PWD antibody, WC1 antibody, WD antibody, WND antibody
- UniProt ID
- P35670
- Observed MW
- 150 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IF: 1:50 - 1:200
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab09849( ATP7B antibody ) at dilution of 1:1000
Immunofluorescence analysis of U2OS cells using FNab09849( ATP7B antibody ). Blue: DAPI for nuclear staining.
- Background
- This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
