Products

ATP2A2 antibody

Synonyms:ATP2B antibody, DAR antibody, DD antibody, SERCA2 antibody
Catalogue No.:FNab09918Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ATP2A2 antibody
Catalogue No.
FNab09918
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
ATP2A2
Alternative Names
ATP2B antibody, DAR antibody, DD antibody, SERCA2 antibody
UniProt ID
P16615
Observed MW
110 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab09918(ATP2A2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab09918(ATP2A2 antibody) at dilution of 1:100
Immunofluorescence analysis of HeLa cells using FNab09918(ATP2A2 antibody). Blue: DAPI for nuclear staining.
Background
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.