ASH2L antibody

Synonyms:ASH2L1 antibody
Catalogue No.:FNab00637Reactivity:Human, Mouse, Rat, Monkey
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ASH2L antibody
Catalogue No.
FNab00637
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
ash2(absent, small, or homeotic)-like(Drosophila)
Alternative Names
ASH2L1 antibody
UniProt ID
Q9UBL3
Observed MW
80 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200
Validated Images
COS-7 cells were subjected to SDS PAGE followed by western blot with FNab00637(ASH2L antibody) at dilution of 1:1000
IP Result of anti-ASH2L (IP:FNab00637, 4ug; Detection:FNab00637 1:500) with COLO 320 cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human gliomas using FNab00637(ASH2L antibody) at dilution of 1:50
Background
Component of the Set1/Ash2 histone methyltransferase(HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.