ASGR1 antibody

Synonyms:ASGP R 1 antibody, ASGPR antibody, ASGPR 1 antibody, Asgpr1 antibody, ASGR1 antibody, asialoglycoprotein receptor 1 antibody, CLEC4H1 antibody, Hepatic lectin H1 antibody, HL 1 antibody, Hs.12056 antibody
Catalogue No.:FNab00635Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ASGR1 antibody
Catalogue No.
FNab00635
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
asialoglycoprotein receptor 1
Alternative Names
ASGP R 1 antibody, ASGPR antibody, ASGPR 1 antibody, Asgpr1 antibody, ASGR1 antibody, asialoglycoprotein receptor 1 antibody, CLEC4H1 antibody, Hepatic lectin H1 antibody, HL 1 antibody, Hs.12056 antibody
UniProt ID
P07306
Observed MW
40 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:1000 - 1:4000; IHC: 1:50 - 1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab00635(ASGR1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab00635( ASGR1 Antibody) at dilution of 1:100
Background
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.