Products
ASGR1 antibody
Category:
Research Area:
Synonyms: | ASGP R 1 antibody, ASGPR antibody, ASGPR 1 antibody, Asgpr1 antibody, ASGR1 antibody, asialoglycoprotein receptor 1 antibody, CLEC4H1 antibody, Hepatic lectin H1 antibody, HL 1 antibody, Hs.12056 antibody | ||
Catalogue No.: | FNab00635 | Reactivity: | Human, Mouse, Rat |
Host: | Rabbit | Tested Application: | ELISA, WB, IHC |
Clonality: | polyclonal | Isotype: | IgG |
- SPECIFICATIONS
- Product Name
- ASGR1 antibody
- Catalogue No.
- FNab00635
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- asialoglycoprotein receptor 1
- Alternative Names
- ASGP R 1 antibody, ASGPR antibody, ASGPR 1 antibody, Asgpr1 antibody, ASGR1 antibody, asialoglycoprotein receptor 1 antibody, CLEC4H1 antibody, Hepatic lectin H1 antibody, HL 1 antibody, Hs.12056 antibody
- UniProt ID
- P07306
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:1000 - 1:4000; IHC: 1:50 - 1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab00635(ASGR1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab00635( ASGR1 Antibody) at dilution of 1:100
- Background
- This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.