Products

Angiopoietin 1 antibody

Synonyms:AGP1 antibody, AGPT antibody, ANG 1 antibody, ANG1 antibody, angiopoietin 1 antibody, ANGPT1 antibody, KIAA0003 antibody
Catalogue No.:FNab00391Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Angiopoietin 1 antibody
Catalogue No.
FNab00391
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
angiopoietin 1
Alternative Names
AGP1 antibody, AGPT antibody, ANG 1 antibody, ANG1 antibody, angiopoietin 1 antibody, ANGPT1 antibody, KIAA0003 antibody
UniProt ID
Q15389
Observed MW
53 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
Immunohistochemistry of paraffin-embedded mouse lung using FNab00391(ANGPT1 Antibody) at dilution of 1:100
Immunohistochemistry of paraffin-embedded human esophagus using FNab00391(ANGPT1 Antibody) at dilution of 1:100
Background
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.