Products

AMPK gamma 1 antibody

Synonyms:AMPK gamma1 antibody, AMPK subunit gamma 1 antibody, AMPKG antibody, PRKAG1 antibody
Catalogue No.:FNab00379Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
AMPK gamma 1 antibody
Catalogue No.
FNab00379
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Alternative Names
AMPK gamma1 antibody, AMPK subunit gamma 1 antibody, AMPKG antibody, PRKAG1 antibody
UniProt ID
P54619
Observed MW
38 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab00379( PRKAG1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab00379( PRKAG1 Antibody) at dilution of 1:50
Background
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.