anti- alpha-synuclein antibody

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Product Information
Product name

anti- alpha-synuclein antibody

Catalogue No.

FNab09891

Size

100µg

Form

liquid

Purification

protein A+G purified

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.)

Background

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

Immunogen Information
Immunogen

synuclein, alpha (non A4 component of amyloid precursor)

Synonyms

Alpha synuclein, NACP, PARK1, PARK4, SNCA

Calculated MW

23 kDa

Application
Specificity

Human, Mouse, Rat

Tested Application

ELISA, IHC, WB

Recommended dilution

WB: 1:500 – 1:2000; IHC: 1:500 – 1:2000

Uniprot information
Uniprot ID

P37840

Images

anti- alpha-synuclein antibody 1

Immunohistochemistry of paraffin-embedded mouse brain using FNab09891(SNCA antibody) at dilution of 1:1000


anti- alpha-synuclein antibody 1

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09891(SNCA antibody) at dilution of 1:1000

Current product's manual: Manual

Protocol may be updated. Please feel free to contact Finetest Team to acquire the latest version.

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Hotline

027-87384275
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