mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab00337(Alpha-1-Antitrypsin antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver using FNab00337(Alpha-1-Antitrypsin antibody) at dilution of 1:50
Background
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.