Products
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Aldolase C antibody
- Product Name
- Aldolase C antibody
- Catalogue No.
- FNab00304
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 6F3
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- aldolase C, fructose-bisphosphate
- Alternative Names
- ALDOC antibody, Aldolase C antibody, Brain type aldolase antibody, Fructose bisphosphate aldolase C antibody
- UniProt ID
- P09972
- Observed MW
- 39 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:5000-1:50000; IHC: 1:50-1:500; IF: 1:20-1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab00304(ALDOC antibody) at dilution of 1:10000
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab00304(ALDOC Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- Background
- Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).
