ALADIN antibody

Synonyms:AAA antibody, AAAS antibody, AAASb antibody, ADRACALA antibody, ADRACALIN antibody, ALADIN antibody, DKFZp586G1624 antibody, GL003 antibody
Catalogue No.:FNab00275Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ALADIN antibody
Catalogue No.
FNab00275
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)
Alternative Names
AAA antibody, AAAS antibody, AAASb antibody, ADRACALA antibody, ADRACALIN antibody, ALADIN antibody, DKFZp586G1624 antibody, GL003 antibody
UniProt ID
Q9NRG9
Observed MW
60 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab00275(AAAS antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded mouse heart using FNab00275(AAAS antibody) at dilution of 1:100
Background
The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.