Products
ACVR1C antibody
- Product Name
- ACVR1C antibody
- Catalogue No.
- FNab00130
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- activin A receptor, type IC
- Alternative Names
- ACVR1C antibody, Activin receptor type 1C antibody, Activin receptor type IC antibody, ACVRLK7 antibody, ALK 7 antibody
- UniProt ID
- Q8NER5
- Observed MW
- 60 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Validated Images
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab00130(ACVR1C antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab00130(ACVR1C antibody) at dilution of 1:100
- Background
- ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
