Products

ACOX1 antibody

Synonyms:ACOX antibody, ACOX1 antibody, AOX antibody, PALMCOX antibody, Palmitoyl CoA oxidase antibody, SCOX antibody
Catalogue No.:FNab00095Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ACOX1 antibody
Catalogue No.
FNab00095
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
acyl-Coenzyme A oxidase 1, palmitoyl
Alternative Names
ACOX antibody, ACOX1 antibody, AOX antibody, PALMCOX antibody, Palmitoyl CoA oxidase antibody, SCOX antibody
UniProt ID
Q15067
Observed MW
74 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:100 - 1:200; IF: 1:50 - 1:200
Validated Images
NCI-H460 were subjected to SDS PAGE followed by western blot with FNab00095(AOX antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab00095(AOX antibody) at dilution of 1:100
Background
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.It has 3 isoforms produced by alternative splicing with the molecular mass of 70-74 kDa and can be cleaved post-translationally into a 50-kDa and a 22-kDa subunit between Val468 and Ala469 (PMID: 10672038).