human brain tissue were subjected to SDS PAGE followed by western blot with FNab00066(ACADS antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using FNab00066(ACADS antibody) at dilution of 1:100
Immunofluorescence analysis of U2OS cells using FNab00066(ACADS antibody). Blue: DAPI for nuclear staining.
Background
This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms.