Anti- 4EBP1 Antibody

  • Specifications
Product Information
Product name

Anti- 4EBP1 Antibody

Alternative name

4E BP1 antibody, 4EBP1 antibody, BP 1 antibody, eIF4E binding protein 1 antibody, EIF4EBP1 antibody, PHAS I antibody,4EBP1 Antibody

Catalogue No.

FNab00006

Size

100μg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

Monoclonal

Isotype

IgG2b

Description

4EBP1 antibody: Mouse Monoclonal antibody to 4EBP1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Background

Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.

Immunogen Information
Immunogen

eukaryotic translation initiation factor 4E binding protein 1

Synonyms

4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I

Calculated MW

12kDa

Application
Specificity

Human, Mouse

Tested Application

ELISA, WB, IHC

Recommended dilution

WB : 1:1000-1:10000;IHC : 1:20-1:200;IF : 1:20-1:200

Uniprot information
Gene Name

4EBP1

Uniprot ID

Q13541

Images

Anti- 4EBP1 Antibody 1

Immunohistochemistry of paraffin-embedded human pancreas slide using FNab00006( 4EBP1 Antibody) at dilution of 1:50


Anti- 4EBP1 Antibody 2

K-562 cells were subjected to SDS PAGE followed by western blot with FNab00006(4EBP1 antibody) at dilution of 1:2000

Service

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Hotline

027-87384275
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