Products
ZW10 antibody
- Product Name
- ZW10 antibody
- Catalogue No.
- FNab09760
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ZW10, kinetochore associated, homolog(Drosophila)
- Alternative Names
- HZW10 antibody, KNTC1AP antibody, ZW10 antibody
- UniProt ID
- O43264
- Observed MW
- 90 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:200-1:2000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09760(ZW10 Antibody) at dilution of 1:1000
- Background
- Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:11590237, PubMed:15485811, PubMed:15824131). Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum(ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER(PubMed:15029241).
