Products
TFE3 antibody
- Product Name
- TFE3 antibody
- Catalogue No.
- FNab08626
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transcription factor binding to IGHM enhancer 3
- Alternative Names
- bHLHe33 antibody, RCCP2 antibody, TFE3 antibody, TFEA antibody, Transcription factor E3 antibody
- UniProt ID
- P19532
- Observed MW
- 65KD
Application
- Tested Applications
- ELISA, WB, IP,IHC
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:500
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab08626(TFE3 antibody) at dilution of 1:1000
IP Result of anti-TFE3 (IP:FNab08626, 4ug; Detection:FNab08626 1:500) with K-562 cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using FNab08626(TFE3 Antibody) at dilution of 1:200
- Background
- Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
