MME,CD10 antibody

Synonyms:Atriopeptidase antibody, CALLA antibody, CD10 antibody, DKFZp686O16152 antibody, Enkephalinase antibody, EPN antibody, membrane metallo endopeptidase antibody, MME antibody, NEP antibody, Neprilysin antibody, Neutral endopeptidase antibody, Neutral endopeptidase 24.11 antibody
Catalogue No.:FNab05232Reactivity:Human, Pig
Host:MouseTested Application:ELISA, IHC, WB
Clonality:monoclonalIsotype:IgG2a
  • SPECIFICATIONS
Product Name
MME,CD10 antibody
Catalogue No.
FNab05232
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG2a
Clone ID
1H6
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
membrane metallo-endopeptidase
Alternative Names
Atriopeptidase antibody, CALLA antibody, CD10 antibody, DKFZp686O16152 antibody, Enkephalinase antibody, EPN antibody, membrane metallo endopeptidase antibody, MME antibody, NEP antibody, Neprilysin antibody, Neutral endopeptidase antibody, Neutral endopeptidase 24.11 antibody
UniProt ID
P08473
Observed MW
90-110 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:500-1:5000; IHC: 1:20-1:200
Validated Images
pig kidney tissue were subjected to SDS PAGE followed by western blot with FNab05232(MME,CD10 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human renal cell carcinoma using FNab05232(MME,CD10 antibody) at dilution of 1:100
Background
MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).This antibody is specific to MME.