IRS2 antibody

Synonyms:Insulin receptor substrate 2 antibody, IRS 2 antibody, IRS2 antibody
Catalogue No.:FNab09769Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
IRS2 antibody
Catalogue No.
FNab09769
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Insulin receptor substrate 2 peptied
Alternative Names
Insulin receptor substrate 2 antibody, IRS 2 antibody, IRS2 antibody
UniProt ID
Q9Y4H2
Observed MW
170 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
rat liver tissue were subjected to SDS PAGE followed by western blot with FNab09769(IRS2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse stomach using FNab09769(IRS2 antibody) at dilution 1:100
Background
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.