Products

FADD antibody

Synonyms:FADD antibody, GIG3 antibody, MORT1 antibody, Protein FADD antibody
Catalogue No.:FNab02941Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, WB, IP
Clonality:polyclonalIsotype:IgG
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Product Name
FADD antibody
Catalogue No.
FNab02941
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Fas(TNFRSF6)-associated via death domain
Alternative Names
FADD antibody, GIG3 antibody, MORT1 antibody, Protein FADD antibody
UniProt ID
Q13158
Observed MW
26 kDa
Application
Tested Applications
ELISA, IHC, WB, IP
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab02941(FADD Antibody) at dilution of 1:1000
IP Result of anti-FADD (IP:FNab02941, 4ug; Detection:FNab02941 1:300) with A549 cells lysate 3040ug.
Immunohistochemistry of paraffin-embedded human lung cancer using FNab02941(FADD antibody) at dilution of 1:50
Background
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
IF: 4.092
Journal:
The International Journal of Biochemistry & Cell Biology
Cited Date:
2017-11-10
Product: