EPCAM antibody

Synonyms:GA733-2 antibody, M1S2 antibody, M4S1 antibody, MIC18 antibody, TACSTD1 antibody, TROP1 antibody
Catalogue No.:FNab09783Reactivity:Human
Host:MouseTested Application:ELISA, WB, IHC
Clonality:monoclonalIsotype:IgG1
  • SPECIFICATIONS
Product Name
EPCAM antibody
Catalogue No.
FNab09783
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG1
Clone ID
3C8
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
epithelial cell adhesion molecule
Alternative Names
GA733-2 antibody, M1S2 antibody, M4S1 antibody, MIC18 antibody, TACSTD1 antibody, TROP1 antibody
UniProt ID
P16422
Observed MW
36 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:1000-1:10000; IHC: 1:50-1:500
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab09783(EPCAM Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab09783(EPCAM Antibody) at dilution of 1:500
Background
Epithelial cell adhesion molecule(EpCAM, CD326) is a type I transmembrane glycoprotein that functions as a homophilic, epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion, EpCAM is also involved in cellular signaling, cell migration, proliferation, and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas, and has become a therapeutic target.(PMID: 20837599; 19249674; 21576002; 22647938)